Genetically damaged sperm

Frequent sexual activity improves the genetic quality of sperm and may help some couples conceive, fertility specialists have found. A study of men attending a fertility clinic revealed that genetic defects in their sperm fell substantially after going on a programme that required them to engage in sexual activity daily for a week. Fertility doctors commonly advise men trying for a baby to abstain from sexual activity for two to three days, because it boosts the number of sperm they produce. The latest finding suggests that men who have healthy sperm counts but poor quality sperm can improve the genetic material in the cells by engaging in sex more often.
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Sperm DNA damage diagnostics: when and why

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Effect of antioxidants on sperm genetic damage.

Semen analysis usually looks at the numbers and the condition of whole sperm. But the authors of a small study in Poland believe the degree of breakage, or fragmentation, in DNA strands in the sperm might be a better indicator of fertility. Men with fragmentation have lower odds of conceiving naturally and through procedures like in vitro fertilization, they write in the International Journal of Impotence Research. Researchers have noticed before that lifestyle factors can influence the level of sperm DNA fragmentation, said Ricardo P.
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Everyday stressors tied to sperm damage

Testicular cancer TC is one of the most treatable of all malignancies and the management of the quality of life of these patients is increasingly important, especially with regard to their sexuality and fertility. Survivors must overcome anxiety and fears about reduced fertility and possible pregnancy-related risks as well as health effects in offspring. There is thus a growing awareness of the need for reproductive counseling of cancer survivors. Studies found a high level of sperm DNA damage in TC patients in comparison with healthy, fertile controls, but no significant difference between these patients and infertile patients. Sperm DNA alterations due to cancer treatment persist from 2 to 5 years after the end of the treatment and may be influenced by both the type of therapy and the stage of the disease.
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As legal access to marijuana continues expanding across the U. New research from Duke Health suggests men in their child-bearing years should also consider how THC could impact their sperm and possibly the children they conceive during periods when they've been using the drug. Much like previous research that has shown tobacco smoke, pesticides, flame retardants and even obesity can alter sperm, the Duke research shows THC also affects epigenetics, triggering structural and regulatory changes in the DNA of users' sperm. Experiments in rats and a study with 24 men found that THC appears to target genes in two major cellular pathways and alters DNA methylation, a process essential to normal development.
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